Antibiotics for treating osteomyelitis in people with sickle cell disease
Background Osteomyelitis (both acute and chronic) is one of the most common infectious complications in people with sickle cell disease. There is no standardized approach to antibiotic therapy and treatment is likely to vary from country to country. Thus, there is a need to identify the efficacy...
| Autor Principal: | Martí-Carvajal, AJ |
|---|---|
| Otros Autores: | Agreda-Pérez, LH, Cortés Jofré, Marcela |
| Formato: | Artículo |
| Idioma: | English |
| Publicado: |
Wiley
2016
|
| Materias: | |
| Acceso en línea: |
Cochrane database of systematic reviews |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: |
Background
Osteomyelitis (both acute and chronic) is one of the most common infectious complications in people with sickle cell disease. There is
no standardized approach to antibiotic therapy and treatment is likely to vary from country to country. Thus, there is a need to identify
the efficacy and safety of different antibiotic treatment approaches for people with sickle cell disease suffering from osteomyelitis.
Objectives
To determine whether an empirical antibiotic treatment approach (monotherapy or combination therapy) is effective and safe as
compared to pathogen-directed antibiotic treatment and whether this effectiveness and safety is dependent on different treatment
regimens, age or setting.
Search strategy
We searched The Group’s Haemoglobinopathies Trials Register, which comprises references identified from comprehensive electronic
database searches and handsearching of relevant journals and abstract books of conference proceedings. We also searched the LILACS
database (1982 to 14 January 2009) and www.clinicaltrials.gov (June 2008).
Date of most recent search of the Haemoglobinopathies Trials Register: 14 November 2008.
Selection criteria
We searched for published or unpublished randomised and quasi-randomised controlled trials.
Data collection and analysis
Each author intended to independently extract data and assess trial quality by standard Cochrane Collaboration methodologies, but
no eligible randomised controlled trials were identified.
Main results
We were unable to find any randomised or quasi-randomised controlled trials on antibiotic treatment approaches for osteomyelitis in
people with sickle cell disease. |
|---|