Hypoglossal Nerve Stimulation: A New Treatment Approach for Obstructive Sleep Apnea. A Review
Introduction: Obstructive Sleep Apnea (OSA) is the most common sleep respiratory disorder. Although Continuous Positive Airway Pressure (CPAP) is the treatment of choice, it has poor adherence. The Hypoglossal Nerve Stimulation (HNS) is being studied as a new therapeutic approach.Objective: To revie...
| Autor Principal: | Pérez García, Irene Camila; Hospital Universitario San Ignacio; Instituto del Corazón |
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| Otros Autores: | Salcedo Betancourt, Juan David; Hospital Universitario San Ignacio; Instituto del Corazón, Ríos Rosado, Elsa Carolina; Hospital Universitario San Ignacio; Instituto del Corazón, Ruiz Morales, Álvaro J.; Pontificia Universidad Javeriana, Ospina García, Juan Camilo; Pontificia Universidad Javeriana, Hidalgo Martínez, Patricia; Pontificia Universidad Javeriana |
| Formato: | info:eu-repo/semantics/article |
| Idioma: | spa |
| Publicado: |
Pontificia Universidad Javeriana
2014
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| Materias: | |
| Acceso en línea: |
http://revistas.javeriana.edu.co/index.php/vnimedica/article/view/16314 |
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| Sumario: |
Introduction: Obstructive Sleep Apnea (OSA) is the most common sleep respiratory disorder. Although Continuous Positive Airway Pressure (CPAP) is the treatment of choice, it has poor adherence. The Hypoglossal Nerve Stimulation (HNS) is being studied as a new therapeutic approach.Objective: To review the pathophysiology of this disorder and the effectivenessand safety of HNS as a treatment for OSA. Methods: Information was retrieved from the database Medline using the search terms: Sleep Apnea, Syndrome; Sleep Apnea, Obstructive; Hypoglossal Nerve; Electrodes, Implanted; Implantable Neurostimulators, and Electric Stimulation Therapy. Results: 267 articles were found, of which 27 met the inclusion and exclusioncriteria. In addition, a secondary search from these articles was performed. The HNS has shown a favorable effectiveness and safety profile with a high adherence as a treatment for OSA. However, it is not recommended for patients with an Apnea-Hypopnea Index >50 since it only causes a partial reduction of the AHI; a less effective result than the one observed with CPAP.Conclusion: The HNS partially improves one of the pathophysiological mechanisms of OSA. In this review, the data shows an acceptable effectiveness and safety profile in short-term, but more research is needed on the long-term effectiveness and safety of HNS as well as the bilateral use of this new therapy and a clinical study comparing it with CPAP. |
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