Skeletal dysplasia and associated risk factors Description of 29 cases reported in 6 hospitals from Bogotá, Cali and Manizales
Objective: Our aim was to conduct an analysis of risk factors from a population with skeletal dysplasia notified in some cities of Colombia in the last eight years. Methods: We conducted a case-control study in several Colombian hospitals participating in the Latin-American Collaborative Study of Co...
Autor Principal: | Rodríguez Guevara, Fernando; Pontificia Universidad Javeriana |
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Otros Autores: | Rueda Jaime, Lili Johana; Pontificia Universidad Javeriana, Zarante Montoya, Ignacio Manuel; Pontificia Universidad Javeriana |
Formato: | info:eu-repo/semantics/article |
Idioma: | spa |
Publicado: |
Pontificia Universidad Javeriana
2010
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Materias: | |
Acceso en línea: |
http://revistas.javeriana.edu.co/index.php/vnimedica/article/view/16072 |
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Sumario: |
Objective: Our aim was to conduct an analysis of risk factors from a population with skeletal dysplasia notified in some cities of Colombia in the last eight years. Methods: We conducted a case-control study in several Colombian hospitals participating in the Latin-American Collaborative Study of Congenital Malformations (ECLAMC, Spanish acronym). For the analysis 29 cases and 85 controls were included.Results: In the quantitative variables we found statistical significance between cases and controls for paternal age, gestational age, number of gestations and birth weight. With regard to qualitative variables, the cases had a higher risk of birth weight less than 2500 g and low birth weight for the gestational age.Conclusions: Skeletal dysplasias are a congenital malformation with a low frequency in the population studied and often lacking of a specific diagnostic. They are associated with advanced paternal age, low birth weight, gestational age and number of gestations. |
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