Red Cell Morphology Interference in Platelet Indices from Patients with Anemia and Low Mean Corpuscular Volume from the IPS Universitaria, Clínica León XIII
Introduction: The microcytosis and poikilocytosis interfere with platelet count in microcytic anemia, which alters the platelet indices determination in hematology analyzers with impedance.Objective: To evaluate the red cell morphology in blood smears to identify those alterations that interfere wit...
| Autor Principal: | Jaramillo Arbeláez, Patricia E.; Universidad de Antioquia-Clínica León XIII |
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| Otros Autores: | Acevedo Toro, Paola A.; Universidad de Antioquia |
| Formato: | info:eu-repo/semantics/article |
| Idioma: | spa |
| Publicado: |
Pontificia Universidad Javeriana
2013
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| Materias: | |
| Acceso en línea: |
http://revistas.javeriana.edu.co/index.php/vnimedica/article/view/16252 |
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| Sumario: |
Introduction: The microcytosis and poikilocytosis interfere with platelet count in microcytic anemia, which alters the platelet indices determination in hematology analyzers with impedance.Objective: To evaluate the red cell morphology in blood smears to identify those alterations that interfere with platelet indices results in patients with microcytic anemia. Materials and Methods: Fifty adult patients hospitalized with heterogeneous microcytic anemia were confirmed through automated full blood count. Red cell and platelet morphology was evaluated in blood films obtained through digital puncture.Results: It was found red cell anisocytosis characterized by 1+ to 2+ of microcytes. There was a correlation between Platelet Distribution Width (PDW) and Mean Platelet Volume (MPV) (p=0,041 and p=0,036 respectively), the small erythrocytes size correlates with MPV and PDW; nevertheless, erythroid morphology doesn’t correlate neither with P-LCR and platelet count. Also, there wasn’t significant difference between erythroid morphology and platelet indices.Conclusions: Platelet indices interpretation in hematology analyzers with impedance isn’t influenced by microcytosis or poikilocytosis in patients with heterogeneous microcytic anemia that present several clinical conditions. |
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