Candida’s species in relation with CD4 counts in HIV-AIDS patients

BACKGROUND: Oral candidiasis is common in HIV(+) patients when their CD4 counts are significantly diminished making the immune system incapable of answer to opportunistic microorganisms as candida, the different candida’s species that are normally found in oral flora in normal conditions are the cau...

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Autor Principal: Garzón Amaya, Catalina; Pontificia Universidad Javeriana
Otros Autores: Gutiérrez Sánchez, Luisa; Pontificia Universidad Javeriana, Salazar Quiroga, Carolina; Pontificia Universidad Javeriana, Barrientos Sánchez, Silvia; Pontificia Universidad Javeriana, Romero Mesa, Carlos Alberto; Pontificia Universidad Javeriana
Formato: info:eu-repo/semantics/article
Idioma: spa
Publicado: Editorial Pontificia Universidad Javeriana 2009
Acceso en línea: http://revistas.javeriana.edu.co/index.php/revUnivOdontologica/article/view/538
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Sumario: BACKGROUND: Oral candidiasis is common in HIV(+) patients when their CD4 counts are significantly diminished making the immune system incapable of answer to opportunistic microorganisms as candida, the different candida’s species that are normally found in oral flora in normal conditions are the causes for the development of oral candidiasis, PURPOSE: An in vitro study was made making an isolation of candida yeasts for the identification of the most common specie that is found in HIV(+) patients that attend the Pontificia Universidad Javeriana Dental School in relation with their CD4 counts. 45 patients were chosen and assigned to 3 groups of 15 patients each according to their CD4 counts, less than 200 cells/mm³, between 201 and 499 cells/mm³ and more than 500 cells/mm³. A sample of plaque was taken from the tongue of each patient and was cultivated in Chromoagar Candida Becton B-dickinsonâ RESULTS: After a week, 29% of the samples were positive for yeasts growth, of these 68% were C. albicans, 19% C. tropicalis and 13% C. krusei. 54% were found in patients with their CD4 counts less than 200 cells/mm³, 31% in patients with CD4 between 201 and 499 cells/mm³ and 15% in those with more than 500 cells/mm³.  The specie most frequently found in the isolations was C. albicans and the growth of the species was found with major frequency in those patients with their CD4 counts low to 200 cells/mm³.