Phenotypic Characterization of Facial Morphology in an African Population with Non-Syndromic Cleft Lip/Palate
Background: Craniofacial shape of individuals with orofacial clefts is different from unaffected ones and is influenced by hereditary factors. It was suggested that the craniofacial morphology of biological parents of affected individuals may differ from the regular population. Objective: Describe...
| Autor Principal: | Borrero Zamudio, Diana Constanza; Pontificia Universidad Javeriana |
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| Otros Autores: | Gutiérrez Ricaurte, Susana Paola; Pontificia Universidad Javeriana, Izaguirre Downing, Daniela Mercedes; Pontificia Universidad Javeriana, Otero Mendoza, Liliana Margarita; Pontificia Universidad Javeriana |
| Formato: | info:eu-repo/semantics/article |
| Idioma: | spa |
| Publicado: |
Editorial Pontificia Universidad Javeriana
2010
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| Acceso en línea: |
http://revistas.javeriana.edu.co/index.php/revUnivOdontologica/article/view/797 |
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| Sumario: |
Background: Craniofacial shape of individuals with orofacial clefts is different from unaffected ones and is influenced by hereditary factors. It was suggested that the craniofacial morphology of biological parents of affected individuals may differ from the regular population. Objective: Describe the parental facial phenotype that may be related to risk of non-syndromic cleft lip/palate (NSCLP) in the offspring in an African population. Methods: 67 frontal and lateral photographs from 80 parents of children with NSCL with or without palate; 70 photographs from a control group were selected. Photos were analyzed through the Vistadent O.C. software and a screen ruler. Results: The frontal view of the facial upper third was smaller in the parental and control groups (64% and 40%). Transversally, the interlimbic distance in the study group was larger (56.7%) than the control group (37.1%) (p=0,02). When comparing cleft side and presence of lateral asymmetry, there was a larger nasal width on the left side (16 parents) and 10 of these had an offspring with left side cleft. Conclusions: Parents of children with NSCLP in this sample of African race showed phenotypic traits that differed from the control group. In the horizontal view, parents had a larger interlimbic distance that may be associated with the risk of having children with NSCLP. Vertically, a smaller facial upper third cannot be taken as a risk factor as has been taken for other race studies, as well as a large nasal width in the African race is not a risk factor, but a common trait in the African race. |
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