KMP-11: proteína 11 de Membrana de Kinetoplástidos
The kinetoplastid membrane protein KMP-11 is a 11kDa glycoprotein, is present on the surface of all stages of parasites life cycle, but is expressed at higher levels in vector insect stages. The characteristics presented by this protein, such as its remarkably high degree of sequence homology amon...
| Autor Principal: | Diez Ortega, Hugo; Laboratorio de Parasitologia Molecular, Departamento de Microbiología, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá |
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| Otros Autores: | López, Manuel Carlos; Laboratorio de Parasitologia Molecular, Departamento de Microbiología, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Thomas, Maricarmen; Laboratorio de Parasitologia Molecular, Departamento de Microbiología, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, Puerta Bula, Concepción; Laboratorio de Parasitologia Molecular, Departamento de Microbiología, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá |
| Formato: | info:eu-repo/semantics/article |
| Idioma: | eng |
| Publicado: |
Pontificia Universidad Javeriana
2004
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| Materias: | |
| Acceso en línea: |
http://revistas.javeriana.edu.co/index.php/scientarium/article/view/5033 |
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| Sumario: |
The kinetoplastid membrane protein KMP-11 is a 11kDa glycoprotein, is present on the surface of all stages of parasites life cycle, but is expressed at higher levels in vector insect stages. The characteristics presented by this protein, such as its remarkably high degree of sequence homology among kinetoplastids, its association to the membrane, as well as to the cytoskeleton and the flagellum, and its immunological reactivity make this protein a potential target for developing chemotherapy or immunotherapy strategies against the diseases caused by these parasites. In this context, here we present the results of the KMP-11 genes study from Trypanosoma rangeli. |
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