Apigenin glycoside: an antioxidant isolated from Alchornea coelophylla pax & k. Hoffm. (euphorbiaceae) leaf extract
An antioxidant flavonoid has been isolated from methanolic leaf extract of Alchornea coelophylla Pax & K. Hoffm. by means of different column chromatography steps with DIAION HP-20 resin and silica gel in combination with analytical high-performance liquid chromatography (HPLC). It was ident...
| Autor Principal: | Martínez, César A; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia. |
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| Otros Autores: | Mosquera, Oscar M; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia., Niño, Jaime; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia. |
| Formato: | info:eu-repo/semantics/article |
| Idioma: | eng |
| Publicado: |
Pontificia Universidad Javeriana
2016
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| Materias: | |
| Acceso en línea: |
http://revistas.javeriana.edu.co/index.php/scientarium/article/view/17808 |
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| Sumario: |
An antioxidant flavonoid has been isolated from methanolic leaf extract of Alchornea coelophylla Pax & K. Hoffm. by means of different column chromatography steps with DIAION HP-20 resin and silica gel in combination with analytical high-performance liquid chromatography (HPLC). It was identified as Apigenin-8-C-(α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside) on the basis of spectroscopic analysis and by comparison with related values reported in the literature. This compound exhibited high in vitro antioxidant activity through DPPH• and ABTS•+ colorimetric assays with IC50 values of 7.528 and 379.7 μg. mL-1, respectively. |
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