Actualización en la comprensión y manejo de la intoxicación por acetaminofén
Acetaminophen poisoning is one of the most frequent causes of acute fulminant hepatic failure and one of the main causes of care in emergency services due to drug intoxication. Recent progress has been made in the pathophysiological understanding, diagnosis and treatment of this clinical entity. The...
Autor Principal: | Castellanos Garzón, Rafael Gustavo |
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Otros Autores: | Barrios Peralta, Elkin Rene, Vides Velásquez, Alberto Adolfo, Olarte, Maria Francisca |
Formato: | info:eu-repo/semantics/article |
Idioma: | spa |
Publicado: |
Pontificia Universidad Javeriana
2018
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Acceso en línea: |
http://revistas.javeriana.edu.co/index.php/vnimedica/article/view/23825 |
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Sumario: |
Acetaminophen poisoning is one of the most frequent causes of acute fulminant hepatic failure and one of the main causes of care in emergency services due to drug intoxication. Recent progress has been made in the pathophysiological understanding, diagnosis and treatment of this clinical entity. The mechanisms of oxidative stress and mitochondrial DNA damage explain the damage caused by this intoxication. This review presents aspects related to the epidemiology, pathophysiological mechanisms, diagnosis and treatment of acetaminophen intoxication. |
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