Integrated use of biomarkers (O : N ratio and acetylcholinesterase inhibition) on aulacomya ater (Molina, 1782) (Bivalvia: Mytilidae) as a criteria for effects of organophosphate pesticide exposition

The effect of residual concentrations of organophosphate pesticide chlorpyrifos (Lorsban 4E) on the activity of the acetylcholinesterase enzyme and oxygen : nitrogen ratio in the mussel Aulacomya ater was analyzed. Toxicity tests show a sensitivity to the pesticide in the bivalve estimated at 16 μg...

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Autor Principal: Führer, Eduardo
Otros Autores: Rudolph, Anny, Espinoza, Claudio, Díaz, Rodrigo, Gajardo, Marisol, Camaño, Nuria
Formato: Artículo
Idioma: English
Publicado: Hindawi Publishing Corporation 2015
Acceso en línea: Journal of Toxicology
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Sumario: The effect of residual concentrations of organophosphate pesticide chlorpyrifos (Lorsban 4E) on the activity of the acetylcholinesterase enzyme and oxygen : nitrogen ratio in the mussel Aulacomya ater was analyzed. Toxicity tests show a sensitivity to the pesticide in the bivalve estimated at 16 μg L−1 ( L C 5 0 − 9 6 h o u r s ). Concentrations between 0.2 and 1.61 μg L−1 were able to inhibit significantly the AChE activity, and concentrations between 0.8 and 1.61 μg L−1 stimulate ammonia excretion and decrease oxygen : ammonia-N (O : N) ratio, with respect to the control group. A. ater proved to be a species sensitive to pesticide exposure and easy to handle in lab conditions. Thus, it is recommended as a bioindicator for use in programs of environmental alertness in the Eastern South Pacific coastal zone.