Synthesis of Hydroxyapatite thin films on PMMA Printed Substrates
Each year millions of people suffer from bone defects resulting from trauma, tumors or bone-related injuries. Therefore there is a need to continuously develop new materials or improve the properties of the materials currently used, for bone replacement or implant applications. Polymethyl methacr...
| Autor Principal: | Sauñi Camposano, Yesenia Haydee |
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| Formato: | info:eu-repo/semantics/masterThesis |
| Idioma: | Inglés |
| Publicado: |
Pontificia Universidad Católica del Perú
2018
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| Materias: | |
| Acceso en línea: |
http://tesis.pucp.edu.pe/repositorio/handle/123456789/9902 |
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| Sumario: |
Each year millions of people suffer from bone defects resulting from trauma, tumors or
bone-related injuries. Therefore there is a need to continuously develop new materials or
improve the properties of the materials currently used, for bone replacement or implant
applications. Polymethyl methacrylate (PMMA) has proven to be a promising alternative
as a material for implants; however, there are still some limitations inherent to this
material, particularly related to its surface properties.
This thesis work is focused on the fabrication of hydroxyapatite (HAp) thin films on the
surface of 3D printed PMMA substrates. 3D printing, particularly the Fused Deposition
Modeling (FDM) technique was used to fabricate PMMA substrates with different surface
porosity levels. FDM technique exhibits the potential for fabricating customized freeform
structures for several applications including craniofacial reconstruction. HAp thin films
were deposited by Radio Frequency Magnetron Sputtering (RFMS) and Ion Beam
Sputtering (IBS) techniques, with a commercial target and an “in house” sintered target,
respectively. A structural, chemical, mechanical, and morphological characterization was
conducted in the generated surfaces by means of X-ray diffraction (XRD), scanning
electron microscopy (SEM), energy dispersive spectroscopy (EDS), and hardness and
roughness measurements.
The results of the XRD analysis revealed an amorphous structure for the films produced by
both RFMS and IBS techniques on the PMMA substrates. The micrographs obtained by
SEM showed a columnar morphology and a low density for the films produced by RFMS;
the same technique revealed a structure of ridges of standing platelets with curved
contours for the IBS deposited films. The amorphous structure and the morphology of the
films, as well as the hardness and roughness can be propitious to improve surface
properties and promote the osseointegration capabilities of PMMA.
This work contributes to the basis for the development of a PMMA implant manufacturing
process using 3D printing and HAp film deposition techniques, with improved
osseointegration properties. |
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