A case of congenital citomegalovirus infection in San Ignacio Hospital, Bogotá

Infections during pregnancy are a major concern bothdue to its incidence and sequelae it might carry, including death. However, clinical suspicion of cytomegalic infection in obstetrics and pediatrics does not correlate with the low confirmation of the disease.In the placenta, congenital CMV infecti...

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Autor Principal: Espinosa, María Alejandra; Hospital Universitario San Ignacio
Otros Autores: Olaya Contreras, Mercedes; Hospital Universitario San Ignacio
Formato: info:eu-repo/semantics/article
Idioma: spa
Publicado: Pontificia Universidad Javeriana 2010
Materias:
Acceso en línea: http://revistas.javeriana.edu.co/index.php/vnimedica/article/view/16012
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Sumario: Infections during pregnancy are a major concern bothdue to its incidence and sequelae it might carry, including death. However, clinical suspicion of cytomegalic infection in obstetrics and pediatrics does not correlate with the low confirmation of the disease.In the placenta, congenital CMV infection produce chronic villitis which is characterized by focal or diffuse chronic inflammation of the villi. Eighty per cent of these cases are asymptomatic, and the rest appear with severe symptoms such as neurological deficits, intrauterine growth retardation, and even death. In fetal autopsies cytomegalic inclusions are typically diagnosed in CMV infection.We report the case of a stillbirth, product of the first pregnancy of an adolescent mother without regular prenatal control, whose autopsy showed the presence of chronic villitis. Viral inclusions in multiple organs such as lungs and pancreas were present, and CMV was confirmed by inmunohistochemestry.