Distribution of serum amylase levels in patients with cutaneous leishmaniasis treated with meglumina antimoniate

The treatment of choice for leishmaniasis is meglumine antimoniate, reporting effects at the pancreatic duct. A study with 90 patients between August 2010 and April 2011 found amylase changes at the beginning, middle and end of treatment at doses of 20 mg/kg/ day. The averages were: weight, 68 kg±9....

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Autor Principal: Rodríguez, Ángela Johanna; Clínica Meta
Otros Autores: Macías, Eva Lucía; Hospital Militar de Oriente
Formato: info:eu-repo/semantics/article
Idioma: spa
Publicado: Pontificia Universidad Javeriana 2016
Materias:
Acceso en línea: http://revistas.javeriana.edu.co/index.php/vnimedica/article/view/16118
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Sumario: The treatment of choice for leishmaniasis is meglumine antimoniate, reporting effects at the pancreatic duct. A study with 90 patients between August 2010 and April 2011 found amylase changes at the beginning, middle and end of treatment at doses of 20 mg/kg/ day. The averages were: weight, 68 kg±9.1, age 24.73±4.45 years, and 28.15±3.97 g of the drug dose. The site of injury was 44,4% in upper limbs. No significant association was found between the variables weight, age and treatment programs. Alteration was present in 49,37% in the middle of treatment and 6,5% at the end. There were significant differences in reported half-amylase treatment on the two doses (p=0.000). In conclusion, control must be performed in serum amylase and rising especially in the middle of treatment.