Inhibición de la actividad hemolítica del veneno de Bothrops atrox por los extractos de Renealmia sp. L. F. y Capsicum c.f pubescens RUIZ & PAV.

Ecuador is one of the most abundant countries in plant species with pharmacological properties, the species Capsicum cf. Pubescens Ruiz & Pav and Renealmia sp, have been taken into account for the present study in order to correct the ethnobotanical knowledge regarding alexite activity aga...

Descripción completa

Autor Principal: Navarrete Espinel, María Andrea
Otros Autores: Zumba Abdo, Magaly Estefanía
Formato: bachelorThesis
Idioma: spa
Publicado: 2017
Materias:
Acceso en línea: http://dspace.ups.edu.ec/handle/123456789/13582
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Sumario: Ecuador is one of the most abundant countries in plant species with pharmacological properties, the species Capsicum cf. Pubescens Ruiz & Pav and Renealmia sp, have been taken into account for the present study in order to correct the ethnobotanical knowledge regarding alexite activity against the bite of Botrops atrox one of the poisonous and abundant species in Ecuador, responsible for a high percentage of ophidian accidents in the Amazon Region. In the present study, the inhibitory or neutralizing capacity of the heptanic, aqueous and alcoholic extracts of C. pubescens and Renealmia sp. on the poison of Bothrops atrox was investigated by qualitative and quantitative assays. As a result, the alcoholic extract presented greater inhibitory capacity with a 1:20 rank (venom/extract) without significant difference between species, using as reference a Minimum Inhibitory Hemolytic Dose in a range of 60-15 ug / mL.