Inhibición de la actividad hemolítica del veneno de Bothrops atrox por los extractos de Tabernaemontana sananho Ruiz & Pav. Y Mucuna cf. elliptica (Ruiz&Pav.) dc.
This research evaluated the anti-hemolytic activity of plant species Mucuna cf. elliptica (Ruiz & Pav.) DC., and Tabernaemontana sananho Ruiz & Pav. that are identified by the inhabitants of the community Wawaim as plants that help to combat the snakebites of the species Bothrops atrox...
| Autor Principal: | Cueva Pungacho, Jenny Verónica |
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| Formato: | bachelorThesis |
| Idioma: | spa |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: |
http://dspace.ups.edu.ec/handle/123456789/13577 |
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| Sumario: |
This research evaluated the anti-hemolytic activity of plant species Mucuna cf.
elliptica (Ruiz & Pav.) DC., and Tabernaemontana sananho Ruiz & Pav. that are
identified by the inhabitants of the community Wawaim as plants that help to combat
the snakebites of the species Bothrops atrox, an ophidian that lives in the Amazon
region and is Responsible for causing most of the accidents.
Total extracts were prepared with solvents of increasing polarity (heptane, ethanol, and
water), and in each case their inhibitory capacity for the hemolytic effect produced by
B. atrox venom on a blood agar-phosphatidylcholine plate was evaluated in vitro,
establishing a minimum hemolytic dose (MIDH) of 15 μg capable of generating a
hemolysis halo of 15.53 mm, which was reduced with doses of 9.4 μg of alcoholic
extract in a proportion 1:7 MIDH-Extract. |
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